SAFETY DATA SHEETS
According to Globally Harmonized System of Classification and Labelling of
Chemicals (GHS) - Sixth revised edition
Version: 1.0
Creation Date: Aug 15, 2017
Revision Date: Aug 15, 2017
1.Identification
1.1 GHS Product identifier
Product name Bromoacetic Acid
1.2 Other means of identification
Product number-
Other names Acetic acid, bromo-
1.3 Recommended use of the chemical and restrictions on use
Identified uses For industry use only.
Uses advised againstno data available
1.4 Supplier's details
1.5 Emergency phone number
Emergency phone number-
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).
2.Hazard identification
2.1 Classification of the substance or mixture
Acute toxicity - Oral, Category 3
Acute toxicity - Dermal, Category 3
Skin corrosion, Category 1A
Skin sensitization, Category 1
Acute toxicity - Inhalation, Category 3
Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1
2.2 GHS label elements, including precautionary statements
Pictogram(s)
Signal word Danger
H301 Toxic if swallowed
H311 Toxic in contact with skin
Hazard statement(s)
H314 Causes severe skin burns and eye damage
H317 May cause an allergic skin reaction
H331 Toxic if inhaled
H400 Very toxic to aquatic life
Precautionary
statement(s)
Prevention
P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P272 Contaminated work clothing should not be allowed out of the workplace.
P271 Use only outdoors or in a well-ventilated area.
P273 Avoid release to the environment.
Response
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER/doctor/…
P321 Specific treatment (see ... on this label).
P330 Rinse mouth.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P312 Call a POISON CENTER/doctor/…if you feel unwell.
P361+P364 Take off immediately all contaminated clothing and wash it before reuse.
P301+P330+P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303+P361+P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water [or
shower].
P363 Wash contaminated clothing before reuse.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P310 Immediately call a POISON CENTER/doctor/…
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and
easy to do. Continue rinsing.
P333+P313 If skin irritation or rash occurs: Get medical advice/attention.
P362+P364 Take off contaminated clothing and wash it before reuse.
P311 Call a POISON CENTER/doctor/…
P391 Collect spillage.
Storage
P405 Store locked up.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
Disposal P501 Dispose of contents/container to ...
2.3 Other hazards which do not result in classification
none
3.Composition/information on ingredients
3.1 Substances
Chemical name Common names and synonyms CAS numberEC numberConcentration
Bromoacetic AcidBromoacetic Acid 79-08-3 none 100%
4.First-aid measures
4.1 Description of necessary first-aid measures
General advice
Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled
If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact
Wash off with soap and plenty of water. Consult a physician.
In case of eye contact
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowed
Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
4.2 Most important symptoms/effects, acute and delayed
Excerpt from ERG Guide 156 [Substances - Toxic and/or Corrosive (Combustible / Water-Sensitive)]: TOXIC; inhalation, ingestion or contact
(skin, eyes) with vapors, dusts or substance may cause severe injury, burns or death. Contact with molten substance may cause severe burns to
skin and eyes. Reaction with water or moist air will release toxic, corrosive or flammable gases. Reaction with water may generate much heat that
will increase the concentration of fumes in the air. Fire will produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water
may be corrosive and/or toxic and cause pollution. (ERG, 2016)
Excerpt from ERG Guide 156 [Substances - Toxic and/or Corrosive (Combustible / Water-Sensitive)]: TOXIC; inhalation, ingestion or contact
(skin, eyes) with vapors, dusts or substance may cause severe injury, burns or death. Contact with molten substance may cause severe burns to
skin and eyes. Reaction with water or moist air will release toxic, corrosive or flammable gases. Reaction with water may generate much heat that
will increase the concentration of fumes in the air. Fire will produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water
may be corrosive and/or toxic and cause pollution. (ERG, 2016)
4.3 Indication of immediate medical attention and special treatment needed, if necessary
Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with
a demand-valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR as necessary. Immediately flush contaminated
eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on left side (head-down position, if
possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention.
/Bromine, methyl bromide, and related compounds/
5.Fire-fighting measures
5.1 Extinguishing media
Suitable extinguishing media
If material on fire or involved in fire: Use water in flooding quantities as fog. Cool all affected containers with flooding quantities of water. Apply
water from as far a distance as possible. Use "alcohol" foam, dry chemical or carbon dioxide. /Bromoacetic acid, solid/
5.2 Specific hazards arising from the chemical
Excerpt from ERG Guide 156 [Substances - Toxic and/or Corrosive (Combustible / Water-Sensitive)]: Combustible material: may burn but does
not ignite readily. Substance will react with water (some violently) releasing flammable, toxic or corrosive gases and runoff. When heated, vapors
may form explosive mixtures with air: indoors, outdoors and sewers explosion hazards. Most vapors are heavier than air. They will spread along
ground and collect in low or confined areas (sewers, basements, tanks). Vapors may travel to source of ignition and flash back. Contact with
metals may evolve flammable hydrogen gas. Containers may explode when heated or if contaminated with water. (ERG, 2016)
Excerpt from ERG Guide 156 [Substances - Toxic and/or Corrosive (Combustible / Water-Sensitive)]: Combustible material: may burn but does
not ignite readily. Substance will react with water (some violently) releasing flammable, toxic or corrosive gases and runoff. When heated, vapors
may form explosive mixtures with air: indoors, outdoors and sewers explosion hazards. Most vapors are heavier than air. They will spread along
ground and collect in low or confined areas (sewers, basements, tanks). Vapors may travel to source of ignition and flash back. Contact with
metals may evolve flammable hydrogen gas. Containers may explode when heated or if contaminated with water. (ERG, 2016)
5.3 Special protective actions for fire-fighters
Wear self-contained breathing apparatus for firefighting if necessary.
6.Accidental release measures
6.1 Personal precautions, protective equipment and emergency procedures
Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel
to safe areas. Avoid breathing dust. For personal protection see section 8.
6.2 Environmental precautions
Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided.
6.3 Methods and materials for containment and cleaning up
Sweep up, place in a bag and hold for waste disposal. Ventilate area and wash spill site after material pickup is complete.
7.Handling and storage
7.1 Precautions for safe handling
Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Avoid exposure - obtain special instructions before use.Provide
appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities
Light sensitive, hygroscopic. Keep tightly closed.
8.Exposure controls/personal protection
8.1 Control parameters
Occupational Exposure limit values
no data available
Biological limit values
no data available
8.2 Appropriate engineering controls
Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.
8.3 Individual protection measures, such as personal protective equipment (PPE)
Eye/face protection
Safety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government
standards such as NIOSH (US) or EN 166(EU).
Skin protection
Wear impervious clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous
substance at the specific workplace. Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique(without
touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable
laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive
89/686/EEC and the standard EN 374 derived from it.
Respiratory protection
Wear dust mask when handling large quantities.
Thermal hazards
no data available
9.Physical and chemical properties
Physical state Colorless to Light Red Liquid/White to Light Red Crystals
Colour Hexagonal or rhomboidal hygroscopic crystals
Odour no data available
Melting point/ freezing point 47-49oC
Boiling point or initial boiling point and boiling range 206-208oC
Flammability no data available
Lower and upper explosion limit / flammability limit no data available
Flash point 113oC (closedoCup)
Auto-ignition temperature no data available
Decomposition temperature no data available
pH no data available
Kinematic viscosity no data available
Solubility In water:miscible
Partition coefficient n-octanol/water (log value) no data available
Vapour pressure 0.119 mm Hg at 25°C
Density and/or relative density 1.934
Relative vapour density no data available
Particle characteristics no data available
10.Stability and reactivity
10.1 Reactivity
no data available
10.2 Chemical stability
Stable under recommended storage conditions.
10.3 Possibility of hazardous reactions
Carboxylic acids, such as BROMOACETIC ACID, donate hydrogen ions if a base is present to accept them. They react in this way with all
bases, both organic (for example, the amines) and inorganic. Their reactions with bases, called "neutralizations", are accompanied by the evolution
of substantial amounts of heat. Neutralization between an acid and a base produces water plus a salt. Carboxylic acids with six or fewer carbon
atoms are freely or moderately soluble in water; those with more than six carbons are slightly soluble in water. Soluble carboxylic acid dissociate to
an extent in water to yield hydrogen ions. The pH of solutions of carboxylic acids is therefore less than 7.0. Many insoluble carboxylic acids react
rapidly with aqueous solutions containing a chemical base and dissolve as the neutralization generates a soluble salt. Carboxylic acids in aqueous
solution and liquid or molten carboxylic acids can react with active metals to form gaseous hydrogen and a metal salt. Such reactions occur in
principle for solid carboxylic acids as well, but are slow if the solid acid remains dry. Even "insoluble" carboxylic acids may absorb enough water
from the air and dissolve sufficiently in it to corrode or dissolve iron, steel, and aluminum parts and containers. Carboxylic acids, like other acids,
react with cyanide salts to generate gaseous hydrogen cyanide. The reaction is slower for dry, solid carboxylic acids. Insoluble carboxylic acids
react with solutions of cyanides to cause the release of gaseous hydrogen cyanide. Flammable and/or toxic gases and heat are generated by the
reaction of carboxylic acids with diazo compounds, dithiocarbamates, isocyanates, mercaptans, nitrides, and sulfides. Carboxylic acids, especially
in aqueous solution, also react with sulfites, nitrites, thiosulfates (to give H2S and SO3), dithionites (SO2), to generate flammable and/or toxic
gases and heat. Their reaction with carbonates and bicarbonates generates a harmless gas (carbon dioxide) but still heat. Like other organic
compounds, carboxylic acids can be oxidized by strong oxidizing agents and reduced by strong reducing agents. These reactions generate heat. A
wide variety of products is possible. Like other acids, carboxylic acids may initiate polymerization reactions; like other acids, they often catalyze
(increase the rate of) chemical reactions.
10.4 Conditions to avoid
no data available
10.5 Incompatible materials
no data available
10.6 Hazardous decomposition products
When heated to decomposition it emits toxic fumes of /bromide./
11.Toxicological information
Acute toxicity
Oral: LD50 Rat oral 177 mg/kg
Inhalation: no data available
Dermal: no data available
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
no data available
Reproductive toxicity
no data available
STOT-single exposure
no data available
STOT-repeated exposure
no data available
Aspiration hazard
no data available
12.Ecological information
12.1 Toxicity
Toxicity to fish: no data available
Toxicity to daphnia and other aquatic invertebrates: EC50; Species: Daphnia magna (Water flea); Conditions: freshwater, renewal, 25°C,
pH >7.0; Concentration: 65000 ug/L for 24 hr; Effect: behavior, equilibrium /formulated product
Toxicity to algae: EC50; Species: Scenedesmus subspicatus (Green algae, log growth phase); Conditions: freshwater, static, 24°C, pH 8.0-
9.3; Concentration: 340 ug/L for 48 hr; Effect: decreased population biomass /formulated product
Toxicity to microorganisms: no data available
12.2 Persistence and degradability
AEROBIC: Bromoacetic acid, present at 2 mg/L, reached 82% of its theoretical biological oxygen demand using the OECD Closed Bottle Test
when using preacclimatized inoculum derived from a Zahn-Wellens test. An OECD Closed Bottle Test performed in the same study using an
unacclimatized inoculum classified the compound as not readily biodegradable(1). Bromoacetic acid was utilized as a carbon source by several
Pseudomonas strains; growth was visible within one week(2).
12.3 Bioaccumulative potential
An estimated BCF of 3.2 was calculated for bromoacetic acid(SRC), using a log Kow of 0.41(1) and a regression-derived equation(2).
According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC).
12.4 Mobility in soil
The Koc of bromoacetic acid is estimated as 39.8(SRC), using a log Kow of 0.41(1) and a regression-derived equation(2). According to a
classification scheme(3), this estimated Koc value suggests that bromoacetic acid is expected to have very high mobility in soil. The pKa of
bromoacetic acid is 2.89(4), indicating that this compound will primarily exist in the anion form in the environment and anions generally do not
adsorb more strongly to soils containing organic carbon and clay than their neutral counterparts(5).
12.5 Other adverse effects
no data available
13.Disposal considerations
13.1 Disposal methods
Product
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not
contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Contaminated packaging
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it
unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible
packaging materials.
14.Transport information
14.1 UN Number
ADR/RID: UN1938IMDG: UN1938IATA: UN1938
14.2 UN Proper Shipping Name
ADR/RID: BROMOACETIC ACID SOLUTION
IMDG: BROMOACETIC ACID SOLUTION
IATA: BROMOACETIC ACID SOLUTION
14.3 Transport hazard class(es)
ADR/RID: 8IMDG: 8IATA: 8
14.4 Packing group, if applicable
ADR/RID: IIIMDG: IIIATA: II
14.5 Environmental hazards
ADR/RID: yesIMDG: yesIATA: yes
14.6 Special precautions for user
no data available
14.7 Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code
no data available
15.Regulatory information
15.1 Safety, health and environmental regulations specific for the product in question
Chemical name Common names and synonyms CAS number EC number
Bromoacetic Acid Bromoacetic Acid 79-08-3 none
European Inventory of Existing Commercial Chemical Substances (EINECS) Listed.
EC Inventory Listed.
United States Toxic Substances Control Act (TSCA) Inventory Listed.
China Catalog of Hazardous chemicals 2015 Listed.
New Zealand Inventory of Chemicals (NZIoC) Listed.
Philippines Inventory of Chemicals and Chemical Substances (PICCS) Listed.
Vietnam National Chemical Inventory Not Listed.
Chinese Chemical Inventory of Existing Chemical Substances (China IECSC)Listed.
16.Other information
Information on revision
Creation Date Aug 15, 2017
Revision Date Aug 15, 2017
Abbreviations and acronyms
CAS: Chemical Abstracts Service
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
IMDG: International Maritime Dangerous Goods
IATA: International Air Transportation Association
TWA: Time Weighted Average
STEL: Short term exposure limit
LC50: Lethal Concentration 50%
LD50: Lethal Dose 50%
EC50: Effective Concentration 50%
References
IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website:
http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
ECHA - European Chemicals Agency, website: https://echa.europa.eu/
Disclaimer: The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this
document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any
guarantee of the properties of the product. We as supplier shall not be held liable for any damage resulting from handling or from contact with the above product.