SAFETY DATA SHEETS
According to Globally Harmonized System of Classification and Labelling of
Chemicals (GHS) - Sixth revised edition
Version: 1.0
Creation Date: Aug 10, 2017
Revision Date: Aug 10, 2017
1.Identification
1.1 GHS Product identifier
Product name 1-bromopropane
1.2 Other means of identification
Product number-
Other names 1-Bromopropane
1.3 Recommended use of the chemical and restrictions on use
Identified uses For industry use only. Solvents (for cleaning or degreasing)
Uses advised againstno data available
1.4 Supplier's details
1.5 Emergency phone number
Emergency phone number-
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).
2.Hazard identification
2.1 Classification of the substance or mixture
Flammable liquids, Category 2
Skin irritation, Category 2
Eye irritation, Category 2
Specific target organ toxicity – single exposure, Category 3
Specific target organ toxicity – single exposure, Category 3
Specific target organ toxicity – repeated exposure, Category 2
Reproductive toxicity, Category 1B
2.2 GHS label elements, including precautionary statements
Pictogram(s)
Signal word Danger
H225 Highly flammable liquid and vapour
Hazard statement(s)
H225 Highly flammable liquid and vapour
H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
H336 May cause drowsiness or dizziness
H360FD
Precautionary
statement(s)
Prevention
P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P233 Keep container tightly closed.
P240 Ground and bond container and receiving equipment.
P241 Use explosion-proof [electrical/ventilating/lighting/...] equipment.
P242 Use non-sparking tools.
P243 Take action to prevent static discharges.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P264 Wash ... thoroughly after handling.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
Response
P303+P361+P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water [or
shower].
P370+P378 In case of fire: Use ... to extinguish.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P321 Specific treatment (see ... on this label).
P332+P313 If skin irritation occurs: Get medical advice/attention.
P362+P364 Take off contaminated clothing and wash it before reuse.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and
easy to do. Continue rinsing.
P337+P313 If eye irritation persists: Get medical advice/attention.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P312 Call a POISON CENTER/doctor/…if you feel unwell.
P314 Get medical advice/attention if you feel unwell.
P308+P313 IF exposed or concerned: Get medical advice/ attention.
Storage
P403+P235 Store in a well-ventilated place. Keep cool.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
Disposal P501 Dispose of contents/container to ...
2.3 Other hazards which do not result in classification
none
3.Composition/information on ingredients
3.1 Substances
Chemical name Common names and synonyms CAS numberEC numberConcentration
1-bromopropane1-bromopropane 106-94-5 none 100%
4.First-aid measures
4.1 Description of necessary first-aid measures
General advice
Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled
Fresh air, rest. Refer for medical attention.
In case of skin contact
Remove contaminated clothes. Rinse skin with plenty of water or shower.
In case of eye contact
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
If swallowed
Rinse mouth.
4.2 Most important symptoms/effects, acute and delayed
Irritating to the eyes, nose, throat, upper respiratory tract, and skin. (USCG, 1999)
4.3 Indication of immediate medical attention and special treatment needed, if necessary
Good curative action is shown by such cysteine derivatives as acetyl-cysteine in poisoning with haloid-alkyls. Dithiol antidotes and other drugs
proved ineffective. /SRP: 1-Bromopropane is metabolized by glutathione S-transferases (at least in rodents). Therefore, N-acetyl-cysteine would
be a good antidote to serve as a precursor in glutathione synthesis and the NAC should be a good antidote./
5.Fire-fighting measures
5.1 Extinguishing media
Suitable extinguishing media
If material on fire or involved in fire: Do not extinguish fire unless flow can be stopped. Use water in flooding quantities as fog. Solid streams of
water may be ineffective. Cool all affected containers with flooding quantities of water. Use "alcohol" foam, dry chemical, or carbon dioxide. Keep
run-off water out of sewers and water sources. /Bromopropanes/
5.2 Specific hazards arising from the chemical
Special Hazards of Combustion Products: Toxic fumes of Hydrogen Bromide Behavior in Fire: 490°C (USCG, 1999)
5.3 Special protective actions for fire-fighters
Wear self-contained breathing apparatus for firefighting if necessary.
6.Accidental release measures
6.1 Personal precautions, protective equipment and emergency procedures
Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel
to safe areas. Avoid breathing dust. For personal protection see section 8.
6.2 Environmental precautions
Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Remove all ignition
sources. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store
and dispose of according to local regulations. Do NOT wash away into sewer.
6.3 Methods and materials for containment and cleaning up
Personal protection: filter respirator for organic gases and vapors adapted to the airborne concentration of the substance. Remove all ignition
sources. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store
and dispose of according to local regulations. Do NOT wash away into sewer.
7.Handling and storage
7.1 Precautions for safe handling
Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Avoid exposure - obtain special instructions before use.Provide
appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities
Fireproof. Separated from strong oxidants and strong bases.Fireproof. Separated from strong oxidants, strong bases.
8.Exposure controls/personal protection
8.1 Control parameters
Occupational Exposure limit values
no data available
Biological limit values
no data available
8.2 Appropriate engineering controls
Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.
8.3 Individual protection measures, such as personal protective equipment (PPE)
Eye/face protection
Safety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government
standards such as NIOSH (US) or EN 166(EU).
Skin protection
Wear impervious clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous
substance at the specific workplace. Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique(without
touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable
laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive
89/686/EEC and the standard EN 374 derived from it.
Respiratory protection
Wear dust mask when handling large quantities.
Thermal hazards
no data available
9.Physical and chemical properties
Physical state Colorless transparent liquid
Colour Colorless liquid
Odour Sweet odor
Melting point/ freezing point -110°C(lit.)
Boiling point or initial boiling point and boiling range 71°C
Flammability Highly flammable. Gives off irritating or toxic fumes (or gases) in a fire.
Lower and upper explosion limit / flammability limit no data available
Flash point 25°C
Auto-ignition temperature 914 deg F (490°C)
Decomposition temperature no data available
pH no data available
Kinematic viscosity 0.489 mPa-s
Solubility In water:2.5 g/L (20 oC)
Partition coefficient n-octanol/water (log value) log Kow = 2.10
Vapour pressure 146 mm Hg ( 20 °C)
Density and/or relative density 1.353
Relative vapour density 4.3 (vs air)
Particle characteristics no data available
10.Stability and reactivity
10.1 Reactivity
no data available
10.2 Chemical stability
Stable under recommended storage conditions.
10.3 Possibility of hazardous reactions
Highly flammable. Gives off irritating or toxic fumes (or gases) in a fire.The vapour is heavier than air and may travel along the ground; distant
ignition possible.Halogenated aliphatic compounds, such as 2-BROMOPROPANE, are moderately or very reactive. Halogenated organics
generally become less reactive as more of their hydrogen atoms are replaced with halogen atoms. Low molecular weight haloalkanes are highly
flammable and can react with some metals to form dangerous products. Materials in this group are incompatible with strong oxidizing and reducing
agents. Also, they are incompatible with many amines, nitrides, azo/diazo compounds, alkali metals, and epoxides. Emits toxic fumes of bromine
when burned.
10.4 Conditions to avoid
no data available
10.5 Incompatible materials
no data available
10.6 Hazardous decomposition products
When heated to decomposition it emits toxic fumes of /hydrogen bromide/.
11.Toxicological information
Acute toxicity
Oral: LD50 Rat oral >2000 mg/kg
Inhalation: LC50 Rat inhalation 253 g/cu m/ 30 minutes
Dermal: no data available
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
no data available
Reproductive toxicity
no data available
STOT-single exposure
no data available
STOT-repeated exposure
no data available
Aspiration hazard
no data available
12.Ecological information
12.1 Toxicity
Toxicity to fish: LC50; Species: Pimephales promelas (Fathead minnow); Conditions: flow through; Concentration: 67.3 mg/L for 96 hr
Toxicity to daphnia and other aquatic invertebrates: no data available
Toxicity to algae: no data available
Toxicity to microorganisms: no data available
12.2 Persistence and degradability
AEROBIC: 1-Bromopropane, present at 100 mg/L, reached 70% of its theoretical BOD in 4 weeks using an activated sludge inoculum at 30
mg/L in the Japanese MITI test(5).
12.3 Bioaccumulative potential
An estimated BCF of 11 was calculated in fish for 1-bromopropane(SRC), using a measured log Kow of 2.10(1) and a regression-derived
equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC). 1-
Bromopropane was classified as having low bioconcentration based on fish accumulation studies (specific data not reported)(4).
12.4 Mobility in soil
Using a structure estimation method based on molecular connectivity indices(1), the Koc of 1-bromopropane can be estimated to be 40(SRC).
According to a classification scheme(2), this estimated Koc value suggests that 1-bromopropane is expected to have very high mobility in soil.
12.5 Other adverse effects
no data available
13.Disposal considerations
13.1 Disposal methods
Product
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not
contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Contaminated packaging
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it
unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible
packaging materials.
14.Transport information
14.1 UN Number
ADR/RID: UN2344IMDG: UN2344IATA: UN2344
14.2 UN Proper Shipping Name
ADR/RID: BROMOPROPANES
IMDG: BROMOPROPANES
IATA: BROMOPROPANES
14.3 Transport hazard class(es)
ADR/RID: 3IMDG: 3IATA: 3
14.4 Packing group, if applicable
ADR/RID: IIIIMDG: IIIIATA: III
14.5 Environmental hazards
ADR/RID: noIMDG: noIATA: no
14.6 Special precautions for user
no data available
14.7 Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code
no data available
15.Regulatory information
15.1 Safety, health and environmental regulations specific for the product in question
Chemical name Common names and synonyms CAS number EC number
1-bromopropane 1-bromopropane 106-94-5 none
European Inventory of Existing Commercial Chemical Substances (EINECS) Listed.
EC Inventory Listed.
United States Toxic Substances Control Act (TSCA) Inventory Listed.
China Catalog of Hazardous chemicals 2015 Listed.
New Zealand Inventory of Chemicals (NZIoC) Listed.
Philippines Inventory of Chemicals and Chemical Substances (PICCS) Listed.
Vietnam National Chemical Inventory Listed.
Chinese Chemical Inventory of Existing Chemical Substances (China IECSC)Listed.
16.Other information
Information on revision
Creation Date Aug 10, 2017
Revision Date Aug 10, 2017
Abbreviations and acronyms
CAS: Chemical Abstracts Service
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
IMDG: International Maritime Dangerous Goods
IATA: International Air Transportation Association
TWA: Time Weighted Average
STEL: Short term exposure limit
LC50: Lethal Concentration 50%
LD50: Lethal Dose 50%
EC50: Effective Concentration 50%
References
IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website:
http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
ECHA - European Chemicals Agency, website: https://echa.europa.eu/
Disclaimer: The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this
document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any
guarantee of the properties of the product. We as supplier shall not be held liable for any damage resulting from handling or from contact with the above product.