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adipic acid 124-04-9 SAFETY DATA SHEETS

2018.09.18 Category:Company profile Share  

  SAFETY DATA SHEETS

  According to Globally Harmonized System of Classification and Labelling of

  Chemicals (GHS) - Sixth revised edition

  Version: 1.0

  Creation Date: Aug 10, 2017

  Revision Date: Aug 10, 2017

  1.Identification

  1.1 GHS Product identifier

  Product name adipic acid

  1.2 Other means of identification

  Product number-

  Other names Hexanedioic acid

  1.3 Recommended use of the chemical and restrictions on use

  Identified uses For industry use only. Processing Aids and Additives

  Uses advised againstno data available

  1.4 Supplier's details

  1.5 Emergency phone number

  Emergency phone number-

  Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

  2.Hazard identification

  2.1 Classification of the substance or mixture

  Eye irritation, Category 2

  2.2 GHS label elements, including precautionary statements

  Pictogram(s)

  Signal word Warning

  Hazard statement(s) H319 Causes serious eye irritation

  Precautionary

  statement(s)

  Prevention

  P264 Wash ... thoroughly after handling.

  P280 Wear protective gloves/protective clothing/eye protection/face protection.

  Response

  P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and

  easy to do. Continue rinsing.

  P337+P313 If eye irritation persists: Get medical advice/attention.

  Storage none

  Disposal

  none

  2.3 Other hazards which do not result in classification

  none

  3.Composition/information on ingredients

  3.1 Substances

  Chemical name Common names and synonyms CAS numberEC numberConcentration

  adipic acid adipic acid 124-04-9 none 100%

  4.First-aid measures

  4.1 Description of necessary first-aid measures

  General advice

  Consult a physician. Show this safety data sheet to the doctor in attendance.

  If inhaled

  Fresh air, rest. Refer for medical attention.

  In case of skin contact

  Remove contaminated clothes. Rinse skin with plenty of water or shower.

  In case of eye contact

  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

  If swallowed

  Rinse mouth. Rest. Refer for medical attention .

  4.2 Most important symptoms/effects, acute and delayed

  Inhalation of vapor irritates mucous membranes of the nose and lungs, causing coughing and sneezing. Contact with liquid irritates eyes and has a

  pronounced drying effect on the skin; may produce dermatitis. (USCG, 1999)

  4.3 Indication of immediate medical attention and special treatment needed, if necessary

  Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with

  a demand-valve resuscitator, bag-valve-mask device, or pocket mask as trained. Perform CPR if necessary. Immediately flush contaminated eyes

  with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on left side (head-down position, if possible) to

  maintain an open airway and prevent aspiration. Keep victim quiet and maintain normal body temperature. Obtain medical attention. /Organic acids

  and related compounds/

  5.Fire-fighting measures

  5.1 Extinguishing media

  Suitable extinguishing media

  Suitable extinguishing media: Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.

  5.2 Specific hazards arising from the chemical

  Behavior in Fire: Melts and may decompose to give volatile acidic vapors of valeric acid and other substances. Dust may form explosive mixture

  with air. (USCG, 1999)

  5.3 Special protective actions for fire-fighters

  Wear self-contained breathing apparatus for firefighting if necessary.

  6.Accidental release measures

  6.1 Personal precautions, protective equipment and emergency procedures

  Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel

  to safe areas. Avoid breathing dust. For personal protection see section 8.

  6.2 Environmental precautions

  Sweep spilled substance into covered plastic containers. If appropriate, moisten first to prevent dusting. Wash away remainder with plenty of

  water.

  6.3 Methods and materials for containment and cleaning up

  Accidental release measures. Personal precautions, protective equipment and emergency procedures: Use personal protective equipment. Avoid

  dust formation. Avoid breathing vapors, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust.;

  Environmental precautions: Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must

  be avoided.; Methods and materials for containment and cleaning up: Pick up and arrange disposal without creating dust. Sweep up and shovel.

  Keep in suitable, closed containers for disposal.

  7.Handling and storage

  7.1 Precautions for safe handling

  Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Avoid exposure - obtain special instructions before use.Provide

  appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2.

  7.2 Conditions for safe storage, including any incompatibilities

  Conditions for safe storage, including any incompatibilities: Keep container tightly closed in a dry and well-ventilated place. Storage class (TRGS

  510): Non Combustible Solids.

  8.Exposure controls/personal protection

  8.1 Control parameters

  Occupational Exposure limit values

  no data available

  Biological limit values

  no data available

  8.2 Appropriate engineering controls

  Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.

  8.3 Individual protection measures, such as personal protective equipment (PPE)

  Eye/face protection

  Safety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government

  standards such as NIOSH (US) or EN 166(EU).

  Skin protection

  Wear impervious clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous

  substance at the specific workplace. Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique(without

  touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable

  laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive

  89/686/EEC and the standard EN 374 derived from it.

  Respiratory protection

  Wear dust mask when handling large quantities.

  Thermal hazards

  no data available

  9.Physical and chemical properties

  Physical state White crystalline powder.

  Colour Monoclinic prisms from ethyl acetate, water, or acetone and petroleum ether

  Odour Odorless

  Melting point/ freezing point 139°C(lit.)

  Boiling point or initial boiling point and boiling range 186°C

  Flammability Combustible.

  Lower and upper explosion limit / flammability limit In air: (dust) 10-15 mg/l

  Flash point 80°C(lit.)

  Auto-ignition temperature 420°C; 232.22°C (USCG, 1999)

  Decomposition temperature no data available

  pH pH of saturated aqueous solution at 25°C = 2.7; pH of 0.1% solution at 25°C = 3.2

  Kinematic viscosity Viscosity of melt: 4.54 cP at 160°C; 2.64 cP at 193°C

  Solubility In water:1.44 g/100 mL (15 oC)

  Partition coefficient n-octanol/water (log value) log Kow = 0.08

  Vapour pressure 1 mm Hg ( 159.5 °C)

  Density and/or relative density 1.36 g/cm3

  Relative vapour density 5 (vs air)

  Particle characteristics no data available

  10.Stability and reactivity

  10.1 Reactivity

  no data available

  10.2 Chemical stability

  Stable under recommended storage conditions.

  10.3 Possibility of hazardous reactions

  Combustible when exposed to heat or flame ...Dust explosion possible if in powder or granular form, mixed with air. If dry, it can be charged

  electrostatically by swirling, pneumatic transport, pouring, etc.ADIPIC ACID is a carboxylic acid. Carboxylic acids donate hydrogen ions if a base

  is present to accept them. They react in this way with all bases, both organic (for example, the amines) and inorganic. Their reactions with bases,

  called "neutralizations", are accompanied by the evolution of substantial amounts of heat. Neutralization between an acid and a base produces

  water plus a salt. Carboxylic acids with six or fewer carbon atoms are freely or moderately soluble in water; those with more than six carbons are

  slightly soluble in water. Soluble carboxylic acid dissociate to an extent in water to yield hydrogen ions. The pH of solutions of carboxylic acids is

  therefore less than 7.0. Many insoluble carboxylic acids react rapidly with aqueous solutions containing a chemical base and dissolve as the

  neutralization generates a soluble salt. Carboxylic acids in aqueous solution and liquid or molten carboxylic acids can react with active metals to

  form gaseous hydrogen and a metal salt. Such reactions occur in principle for solid carboxylic acids as well, but are slow if the solid acid remains

  dry. Even "insoluble" carboxylic acids may absorb enough water from the air and dissolve sufficiently in it to corrode or dissolve iron, steel, and

  aluminum parts and containers. Carboxylic acids, like other acids, react with cyanide salts to generate gaseous hydrogen cyanide. The reaction is

  slower for dry, solid carboxylic acids. Insoluble carboxylic acids react with solutions of cyanides to cause the release of gaseous hydrogen cyanide.

  Flammable and/or toxic gases and heat are generated by the reaction of carboxylic acids with diazo compounds, dithiocarbamates, isocyanates,

  mercaptans, nitrides, and sulfides. Carboxylic acids, especially in aqueous solution, also react with sulfites, nitrites, thiosulfates (to give H2S and

  SO3), dithionites (SO2), to generate flammable and/or toxic gases and heat. Their reaction with carbonates and bicarbonates generates a harmless

  gas (carbon dioxide) but still heat. Like other organic compounds, carboxylic acids can be oxidized by strong oxidizing agents and reduced by

  strong reducing agents. These reactions generate heat. A wide variety of products is possible. Like other acids, carboxylic acids may initiate

  polymerization reactions; like other acids, they often catalyze (increase the rate of) chemical reactions. Behavior in Fire: Melts and may decompose

  to give volatile acidic vapors of valeric acid and other substances.

  10.4 Conditions to avoid

  no data available

  10.5 Incompatible materials

  Incompatible materials: Strong oxidizing agents.

  10.6 Hazardous decomposition products

  Melts and may decompose to give volatile acidic vapors of valeric acid and other substances.

  11.Toxicological information

  Acute toxicity

  Oral: LD50 Mouse oral 1900 mg/kg /From table/

  Inhalation: Rat: inhalation: no effect level: 126 g/L, 15 x 6 hr (as in source)

  Dermal: no data available

  Skin corrosion/irritation

  no data available

  Serious eye damage/irritation

  no data available

  Respiratory or skin sensitization

  no data available

  Germ cell mutagenicity

  no data available

  Carcinogenicity

  no data available

  Reproductive toxicity

  no data available

  STOT-single exposure

  no data available

  STOT-repeated exposure

  no data available

  Aspiration hazard

  no data available

  12.Ecological information

  12.1 Toxicity

  Toxicity to fish: LC50; Species: Pimephales promelas (fathead minnow); Conditions: /static bioassay/; Concentration: >300 mg/L for 1 hr

  Toxicity to daphnia and other aquatic invertebrates: no data available

  Toxicity to algae: no data available

  Toxicity to microorganisms: no data available

  12.2 Persistence and degradability

  AEROBIC: Results of biological screening tests indicate that adipic acid is readily biodegradable(1). Adipic acid, present at 100 mg/L, reached

  81% of its theoretical BOD in 2 weeks using an activated sludge inoculum at 30 mg/L in the Japanese MITI test(2). In study with 10 participating

  laboratories using OECD 301E (ready biodegradability test), all laboratories observed a ready biodegradability of adipic acid with a degradation

  of at least 86% and an average degradation of 96.6% after 19 days(1). In an aerobic modified Sturm test (CO2 evolution) according to OECD

  301B guideline, adipic acid was degraded by 91% in terms of CO2 evolution after a period of 28 days(1). In a closed bottle test (OECD 301D),

  83% of the adipic acid was degraded after 30 days(1). In a test according to the modified OECD screening test (OECD 301E), 96% (related to

  DOC) was degraded after a period of 19 days(1). In four biodegradability screening tests that were designed as models for degradability in

  surface water, the results ranged from 92% of theoretical BOD in 14 days to 83% in 30 days(3,4). In 5 tests designed to simulate treatment plants,

  results ranged from 99% DOC removal in 1 day to 92% of theoretical BOD in 14 days(3-5). In a systematic screening procedure after a 5-10 hr

  lag, 50-75% of theoretical BOD of adipic acid was obtained in 90-100 hr(6). Adipic acid was rapidly degraded in a river die-away test using

  Main River (Germany) water(5); 50% and 90% degradation being achieved in 3.5 and 7 days, respectively, at concentration levels of 700

  mg/L(5). The Afnor test, which was designed to simulate degradation in polluted river water, gave a 5 day BOD of 36% of theoretical(7).

  12.3 Bioaccumulative potential

  An estimated BCF of 3 was calculated in fish for adipic acid(SRC), using a log Kow of 0.08(1) and a regression-derived equation(2). According

  to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC).

  12.4 Mobility in soil

  Using a structure estimation method based on molecular connectivity indices(1), the Koc of adipic acid can be estimated to be 24(SRC).

  According to a classification scheme(2), this estimated Koc value suggests that adipic acid is expected to have very high mobility in soil. The pKa

  values of adipic acid's two acid groups are 4.44 and 5.44(3), indicating that this compound will exist almost entirely in the anion form and anions

  generally do not adsorb more strongly to soils containing organic carbon and clay than their neutral counterparts(4).

  12.5 Other adverse effects

  no data available

  13.Disposal considerations

  13.1 Disposal methods

  Product

  The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not

  contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.

  Contaminated packaging

  Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it

  unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible

  packaging materials.

  14.Transport information

  14.1 UN Number

  ADR/RID: UN1993IMDG: UN1993IATA: UN1993

  14.2 UN Proper Shipping Name

  ADR/RID: FLAMMABLE LIQUID, N.O.S.

  IMDG: FLAMMABLE LIQUID, N.O.S.

  IATA: FLAMMABLE LIQUID, N.O.S.

  14.3 Transport hazard class(es)

  ADR/RID: 3IMDG: 3IATA: 3

  14.4 Packing group, if applicable

  ADR/RID: IIIIMDG: IIIIATA: III

  14.5 Environmental hazards

  ADR/RID: noIMDG: noIATA: no

  14.6 Special precautions for user

  no data available

  14.7 Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code

  no data available

  15.Regulatory information

  15.1 Safety, health and environmental regulations specific for the product in question

  Chemical name Common names and synonyms CAS number EC number

  adipic acid adipic acid 124-04-9 none

  European Inventory of Existing Commercial Chemical Substances (EINECS) Listed.

  EC Inventory Listed.

  United States Toxic Substances Control Act (TSCA) Inventory Listed.

  China Catalog of Hazardous chemicals 2015 Not Listed.

  New Zealand Inventory of Chemicals (NZIoC) Listed.

  Philippines Inventory of Chemicals and Chemical Substances (PICCS) Listed.

  Vietnam National Chemical Inventory Listed.

  Chinese Chemical Inventory of Existing Chemical Substances (China IECSC)Listed.

  16.Other information

  Information on revision

  Creation Date Aug 10, 2017

  Revision Date Aug 10, 2017

  Abbreviations and acronyms

  CAS: Chemical Abstracts Service

  ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road

  RID: Regulation concerning the International Carriage of Dangerous Goods by Rail

  IMDG: International Maritime Dangerous Goods

  IATA: International Air Transportation Association

  TWA: Time Weighted Average

  STEL: Short term exposure limit

  LC50: Lethal Concentration 50%

  LD50: Lethal Dose 50%

  EC50: Effective Concentration 50%

  References

  IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home

  HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm

  IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/

  eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website:

  http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en

  CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple

  ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp

  ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg

  Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp

  ECHA - European Chemicals Agency, website: https://echa.europa.eu/

  Disclaimer: The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this

  document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any

  guarantee of the properties of the product. We as supplier shall not be held liable for any damage resulting from handling or from contact with the above product.